P.169 Tissue plasminogen activator in addition to twist drill drainage as a treatment for chronic subdural hematomas – a descriptive analysis

Background: Current literature provides little consensus on universal guidelines for first-line treatment of chronic subdural hematomas (cSDH). However, administration local tissue plasminogen activator (tPA) may enhance the traditional method twist drill drainage (TDD). The study aims to explore efficacy TDD with and without tPA, at achieving clinically relevant (200mL) reducing recurrence cSDH. Methods: A retrospective review patients (N=34) cSDH is presented. Patients who received tPA (n=17) were identified matched, based primarily age hematoma volume, a control group (n=17), tPA. Variables interest include initial volume drained, length stay, rates. Descriptive analysis was run. Results: Average 74.6 76% male. Mean volumes cohort 381.6mL 151.3mL. addition resulted in nearly double (1.9x) amount had low rates (12.5%). failed result rate 52.9%. stay differed by two days (9.71 tPA; 7.71 control). Conclusions: effective treating our population.